Muscle Contractility and Cell Motility
نویسندگان
چکیده
1Department of Physiology, Wayne State University School of Medicine, Detroit, MI 48201, USA 2Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA 3Department of Biomedical Sciences, Florida Atlantic University Charles E. Schmidt College of Medicine, Boca Raton, FL 33431, USA 4Department of Neuroscience, Clinical Neurophysiology, Uppsala University, 751 85 Uppsala, Sweden
منابع مشابه
α-Actinin-4 Is Essential for Maintaining the Spreading, Motility and Contractility of Fibroblasts
BACKGROUND α-Actinins cross-link actin filaments, with this cross-linking activity regulating the formation of focal adhesions, intracellular tension, and cell migration. Most non-muscle cells such as fibroblasts express two isoforms, α-actinin-1 (ACTN1) and α-actinin-4 (ACTN4). The high homology between these two isoforms would suggest redundancy of their function, but recent studies have sugg...
متن کاملIn a non-human primate model, aging disrupts the neural control of intestinal smooth muscle contractility in a region-specific manner
BACKGROUND Incidences of gastrointestinal (GI) motility disorders increase with age. However, there is a paucity of knowledge about the aging mechanisms leading to GI dysmotility. Motility in the GI tract is a function of smooth muscle contractility, which is modulated in part by the enteric nervous system (ENS). Evidence suggests that aging impairs the ENS, thus we tested the hypothesis that s...
متن کاملCELL MOTILITY Historical Development of Cell Motility
In the first half of the 20 century, it was generally accepted that myosin and actin are proteins specific for muscle, and muscle contractility is a specific interaction of actin, myosin and ATP. It came as a surprise when in 1954 Hoffmann-Berling reported that water-glycerol extracted amnion fibroblasts contract upon addition of ATP. Figures CM1a and 1b show that the elongated fibroblast cells...
متن کاملThe effect of aqueous extract of pomegranate seed on rat uterine smooth muscle contractility
Introduction: Considering the importance of uterine contractions in uterus retraction and reducing post-partum hemorrhage and the current findings on the effect of the alcoholic extract of pomegranate seed on the uterine contractility, only few studies were made on this issue. In the present study the cumulative effect of the aqueous extract of pomegranate seed on the uterine smooth muscle c...
متن کاملMechanics of cytogels I: oscillations in physarum.
The contractility of actomyosin gels is the basis for a variety of cellular motility phenomena. We present here a mechanical analysis of contractile gels. By making certain hypotheses on the chemical regulation of cytogel contraction we formulate a model for the rhythmic contractions of plasmodia in the slime mold Physarum polycephalum which is in accord with a number of experimental observations.
متن کاملSulphonylurea receptors differently modulate ICC pacemaker Ca2+ activity and smooth muscle contractility.
Appropriate gastrointestinal motility is essential to properly control the body energy level. Intracellular Ca2+ ([Ca2+]i) oscillations in interstitial cells of Cajal (ICCs; identified with c-Kit immunoreactivity) are considered to be the primary mechanism for the pacemaker activity in gastrointestinal motility. In the present study, RT-PCR examinations revealed predominant expression of the ty...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
دوره 2012 شماره
صفحات -
تاریخ انتشار 2012